Reply to USB not recognized

I've had few issues with the S4. Now, my computer doesn't recognize the S4. It's saying USB not recognized. Is it possibly a sound card issue? Since the last time I played, Windows updated itself. I installed iTunes. I had this happen and did a system restore. It reverted back to 10 days ago, when I had no problems, and the computer won't recognize the USB. Nothing has changed! This is frustrating.