Reply to No sound from S4

So I was messing around with the new MF mapping and everything was working fine. I got up and did something else then came back and tried to watch a youtube video, but there was no sound. I tried another video, no sound. I played a song in Traktor, no sound. This is out of headphones and both TRS and RCA mains on the back. I've tried every cue possibility, two separate sets of headphones and have confirmed the headphones and speakers work.

The LED meters on the channel faders are working, but the LED's on the main volume meter are not working. If I turn the main volume up in the S4 software the red LED's for clipping will light up on the controller, but there's no blue LED's, just red and no sound. If I change the audio to built in I get sound through the laptop speakers.

I've rebooted twice and nothing's seemed to work. I have a show on Monday. Any ideas?